Content

The course deals with various signal transduction pathways in the cell. Effects of ligand regulated ion channels, G-protein coupled receptors and receptor-tyrosine kinases and examples on other phylogenetically conserved signal pathways are described. Emphasis is put on signal transduction in the central and peripheral nervous system. Signal transduction in the immune system, the coupling between the immune system and the nervous system, neuroendocrine signaling and the effects of toxins, pharmacological substances and various diseases on signal transduction are presented. Specific systems dealing with memory and learning are also studied. Methods for studies on cell signaling in invertebrates, vertebrates and in vitro model systems are described. The course is useful for advanced studies in biology or chemistry (neurochemistry, biochemistry or medical chemistry) or for work in the pharmaceutical industry.

 

The course is composed as follows

Theory                                                   8 credits
Independent literature exercise       7 credits

Apply to the course here.


Literature

Signal Transduction (Eds. BD Gomperts, IM Kramer, PER Tatham), Elsevier Academic Press, 2009 (Akademibokhandeln, Stockholm Univ.), also review articles, other material handed out by the teachers and your own search in PubMed

 

Entry requirements

Chemistry 60 credits, basic level, of which at least 7.5 credits in biochemistry or 60 credits in biology, basic level. In addition at least 15 credits in either neurochemistry, molecular neurobiology, molecular life sciences or medical chemistry, or corresponding knowledge. English B.


For more information please contact associate professor Anna-Lena Ström